Renewing the Field

Renewing the Field

Nurturing the Next Generation of Infectious Disease Physician-Scientists

Renewing the Field

Nurturing the Next Generation of Infectious Disease Physician-Scientists

The COVID-19 pandemic highlighted the importance of having a robust workforce of skilled infectious disease physicians and researchers. They played a vital role in vaccine development, understanding the virus’s behavior, diagnosing and treating patients, and studying its transmission.

To cultivate a vibrant field that continues to flourish and attract the sharpest and brightest minds, the division of infectious diseases and geographic medicine prioritizes mentoring and nurturing the next generation of infectious disease physician-scientists. When another pandemic happens, these emerging new scientists will be the ones on the front lines tasked with safeguarding the public’s health.

Many of the Infectious Diseases Fellows gain clinical experience, connecting with patients and helping them live healthier lives before transitioning to become postdoctoral trainees in laboratory collaborations where they don their creative hats and delve into the depths of exploration. A comprehensive understanding of both clinical and research aspects prepares the trainees for leadership roles as physician-scientists.

Mentors provide both the space and guidance for trainees to engage creatively with the work and pursue innovative and novel solutions to pressing health problems, while also actively assisting them in securing National Institutes of Health grants and other sources of funding.

These grants serve as a crucial milestone, enabling trainees to establish their research programs and replenish the infectious disease field with new and exciting findings.

This year, four trainees stand out, having received top scores for their grant proposals on the first try, an “exceedingly rare” achievement, according to John Scroggs, senior administrative division director. In their own words, the four profiles that follow reflect the trainees’ exceptional abilities and the quality of mentorship they receive, as well as examples of how they recharge, renew, and stave off burnout in a rigorous and competitive industry.

“They are going to be the next generation of the best of the best,” Scroggs says.

Arjun Rustagi, MD, PhD

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, Postdoctoral Research Fellow, Blish Lab

Arya Khosravi, MD, PhD

Postdoctoral Research Fellow, Bollyky Lab

Karen B. Jacobson, MD, MPH

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, The Stephen Bechtel Endowed Fellow in Pediatric Translational Medicine, Postdoctoral Medical Fellow, The Jagannathan Lab

Joelle I. Rosser, MD

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, Faculty Fellow, Center for Innovation and Global Health, Postdoctoral Research Fellow, Luby Lab

Arjun Rustagi, MD, PhD

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, Postdoctoral Research Fellow, Blish Lab

Arya Khosravi, MD, PhD

Postdoctoral Research Fellow, Bollyky Lab

Karen B. Jacobson, MD, MPH

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, The Stephen Bechtel Endowed Fellow in Pediatric Translational Medicine, Postdoctoral Medical Fellow, The Jagannathan Lab

Joelle I. Rosser, MD

Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, Faculty Fellow, Center for Innovation and Global Health, Postdoctoral Research Fellow, Luby Lab

Arjun Rustagi, MD, PhD

Research focus: Reproducing SARS-CoV-2 infection of the human lung in the lab, in order to understand the types of lung inflammation caused by viruses and how to stop them.

How the research advances the field: Identified several pathways that allow SARS-CoV-2’s entry into cells, and determined unexpected cellular targets in the human lung, including macrophages. These findings present new therapeutic targets to reduce SARS-CoV-2 infection and lung inflammation.

Published: 37 publications

Funding: Mentored Career Development Award (K08) from the National Institute of Allergy and Infectious Diseases: $772,000 over four years

Arjun Rustagi, MD, PhD, and Catherine Blish, MD, PhD

Arjun Rustagi, MD, PhD, and Catherine Blish, MD, PhD

Arjun Rustagi, MD, PhD

Research focus: Reproducing SARS-CoV-2 infection of the human lung in the lab, in order to understand the types of lung inflammation caused by viruses and how to stop them.

How the research advances the field: Identified several pathways that allow SARS-CoV-2’s entry into cells, and determined unexpected cellular targets in the human lung, including macrophages. These findings present new therapeutic targets to reduce SARS-CoV-2 infection and lung inflammation.

Published: 37 publications

Funding: Mentored Career Development Award (K08) from the National Institute of Allergy and Infectious Diseases: $772,000 over four years

Arjun is the quintessential triple threat: a clinician scientist who excels in research, teaching, and clinical care. He is a generous collaborator and teacher, working with several other laboratories on complex infection models and training many individuals on virology and immunology. He is clearly a leader and ready to run his own group.

— Catherine Blish, MD, PhD, George E. and Lucy Becker Professor of Medicine

The power of mentorship: Having Catherine as a mentor has been essential. She connected me to collaborators and provided opportunities for me to build research infrastructure at Stanford. When the university shut down during the pandemic, she helped me logistically continue my biobank and BSL3 work.

What the future holds: Looking for a permanent job as a physician-scientist, ideally in the Bay Area, where my partner is also a physician-scientist.

Takeaways from the pandemic: The COVID-19 pandemic has shown us that science in a vacuum or shared only among scientists misses an opportunity to inform the public and help nonscientists think about complex biomedical concepts. I am inspired by programs like Radiolab that mix scientific concepts with audio and visual arts. To help the public better understand my work, I teamed up with art students who helped me translate my main scientific project (studying lung inflammation that happens in response to infection) into artistic concepts.

Preference: Clinical or research? In college, I initially could not decide. Then, the summer before senior year I joined a program working with students in Arusha, Tanzania, to teach basic HIV biology. As I spent time with people living with HIV in the community, I felt that with HIV and infectious disease, I could blend my interests in clinical medicine and basic science and have a fulfilling career. I then worked in a biomedical lab for a couple of years while I applied to MD/PhD programs.

Preventing physician burnout: This is really hard. Our lab has regular social events and retreats, usually overnight at a house in Sonoma or along the coast north of San Francisco. These retreats provide an annual opportunity to take stock. I also benefit from talking and interacting in person with other postdocs and fellows in the lab about the intersection of science, medicine, family, and maintaining balance.

Unwinding with the family: Bike rides through Golden Gate Park with my daughters or playing ultimate Frisbee in the park or on the beach; car camping and trying new restaurants.

Hobbies: Listening to music and podcasts; playing the piano and saxophone; gardening; tending to orchids and my aquarium.

Arya Khosravi, MD, PhD

Research focus: Host-microbial interactions. Specifically, I am studying how some bacteria partner with a virus to establish an ecological niche and cause chronic infections, which are very difficult to treat and are a major cause of suffering and even death.

How the research advances the field: Provides insight into the pathophysiology of chronic infections, allowing for the development of more effective diagnostic and therapeutic interventions.

Published: Three publications (1 article, 2 reviews) while at Stanford; 10 other publications previously

Funding: Cystic Fibrosis Foundation, Doris Duke Charitable Foundation

Paul Bollyky, MD, PhD (left), and Arya Khosravi, MD, PhD

Paul Bollyky, MD, PhD (left), and Arya Khosravi, MD, PhD

Arya Khosravi, MD, PhD

Research focus: Host-microbial interactions. Specifically, I am studying how some bacteria partner with a virus to establish an ecological niche and cause chronic infections, which are very difficult to treat and are a major cause of suffering and even death.

How the research advances the field: Provides insight into the pathophysiology of chronic infections, allowing for the development of more effective diagnostic and therapeutic interventions.

Published: Three publications (1 article, 2 reviews) while at Stanford; 10 other publications previously

Funding: Cystic Fibrosis Foundation, Doris Duke Charitable Foundation

Arya is meticulous, rigorous, and committed to excellence in both the clinic and the lab. He is an outstanding physician-scientist.

— Paul Bollyky, MD, PhD, associate professor of infectious diseases and of microbiology and immunology

Why a career as a physician-scientist? In undergrad, I got a job washing glassware in a lab focused on bacteria that cause infections. The principal investigator and lab members included me in discussions and explained to me what they were studying and why, as well as the methods by which they pursued their studies. I attended clinical rounds and got to see how the same bacteria we were studying in the lab were causing disease in patients. I was hooked. This was exciting, precise work that allowed me to be creative and work alongside passionate and incredibly intelligent individuals while at the same time offering the possibility of providing a significant impact on patient outcomes.

When I eventually started my own project, the lab members helped me understand the difference between statistically significant and meaningful data as well as taught me to be my own harshest critic. They also instilled the value that the purpose of science is to advance knowledge and our understanding of life.

Preference: Clinical or research? Research. It provides me more opportunities to be creative and explore ideas. I very much appreciate patient care and feel my time spent on service is more productive and possibly more meaningful than time in the lab. However, there is a lot of repetition. We often see similar cases and have near-identical discussions with the primary teams calling daily for consultations. In contrast, the questions I am trying to answer in the lab can change drastically from week to week. It’s rewarding to watch a project or idea evolve over time.

What do you love about the job? Allows me to be curious and connect dots. It’s fun when immunology intersects with microbiology, metabolism, ecology, and even philosophy.

Preventing burnout: When I am not in the lab, I am sleeping or watching TV shows to unwind. When I can make time, I enjoy reading and woodworking.

Karen B. Jacobson, MD, MPH

Research focus: Global Health, SARS-CoV-2, Malaria: Studies the natural history, epidemiology, and long-term effects of COVID-19. Most recently, studying the effects of SARS-CoV-2 infection in pregnancy on infant growth and development in Uganda.

How the research advances the field: By leveraging a cohort of pregnant women enrolled in malaria clinical trials in eastern Uganda, my colleagues and I were able to retrospectively document the spread of SARS-CoV-2 during the first pandemic waves when it was spreading undetected due to a lack of available testing. After the first Omicron wave in early 2022, nearly 100% of the cohort had been exposed. The data also hinted that there may be an association between COVID-19 in pregnancy and shorter height in infancy, which has not previously been reported. Further research with larger sample sizes is needed to confirm this finding. Next, further research to examine the mechanisms by which COVID-19 in pregnancy, with and without malaria infection, can adversely affect fetal and infant development, and how vaccination can potentially mitigate these effects.

Funding: K23, National Institute of Allergy and Infectious Diseases, $192,000 per year for 5 years (pending); Burroughs Wellcome Fund/ASTMH Postdoctoral Fellowship in Tropical Infectious Diseases; NIH T32; Stephen Bechtel Endowed Fellowship in Pediatric Translational Medicine; Thrasher Early Career Award recipient.

Prasanna Jagannathan, MD, and Karen B. Jacobson, MD

Paul Bollyky, MD, PhD (left), and Arya Khosravi, MD, PhD

Paul Bollyky, MD, PhD (left), and Arya Khosravi, MD, PhD

Karen B. Jacobson, MD, MPH

Research focus: Global Health, SARS-CoV-2, Malaria: Studies the natural history, epidemiology, and long-term effects of COVID-19. Most recently, studying the effects of SARS-CoV-2 infection in pregnancy on infant growth and development in Uganda.

How the research advances the field: By leveraging a cohort of pregnant women enrolled in malaria clinical trials in eastern Uganda, my colleagues and I were able to retrospectively document the spread of SARS-CoV-2 during the first pandemic waves when it was spreading undetected due to a lack of available testing. After the first Omicron wave in early 2022, nearly 100% of the cohort had been exposed. The data also hinted that there may be an association between COVID-19 in pregnancy and shorter height in infancy, which has not previously been reported. Further research with larger sample sizes is needed to confirm this finding. Next, further research to examine the mechanisms by which COVID-19 in pregnancy, with and without malaria infection, can adversely affect fetal and infant development, and how vaccination can potentially mitigate these effects.

Funding: K23, National Institute of Allergy and Infectious Diseases, $192,000 per year for 5 years (pending); Burroughs Wellcome Fund/ASTMH Postdoctoral Fellowship in Tropical Infectious Diseases; NIH T32; Stephen Bechtel Endowed Fellowship in Pediatric Translational Medicine; Thrasher Early Career Award recipient.

Karen is a rising superstar in global maternal and child health. She is well on her way to an outstanding career as a translational scientist in infectious diseases.

— Prasanna Jagannathan, MD, assistant professor of medicine and of microbiology and immunology

The power of mentorship: I have been very lucky to have Dr. Jagannathan as my primary research mentor. He is supportive, enthusiastic, and always available to his trainees, and has cultivated a collaborative yet rigorous lab atmosphere. I feel lucky to have worked with him and learned from his example.

What the future holds: In fall 2023, I joined the Vaccine Study Center within the division of research at Kaiser Permanente Northern California, based in Oakland, as a research faculty member.

Preference: Clinical or research? Both! I prefer to spend most of my time on research because I like to think about the bigger picture, but I think it’s essential to maintain some patient contact and have those personal connections in order to keep a grounded perspective and remember why the bigger picture is so important.

Why a career as a physician-scientist? I knew I wanted to be an infectious disease physician and researcher before going to medical school. The medicine part has always interested me, but I’ve also been intrigued by the societal impact of infections. Pathogens have shaped the course of human history and seem to lay bare so much of our social and political rifts, with infections like HIV, Ebola, and of course COVID-19 more recently. The advances we’ve seen just in the last century — antibiotics, vaccines, a SARS-CoV-2 vaccine developed in less than a year — are astounding. I think it’s such an interesting and important field!

Avoiding burnout: I recently had the opportunity to attend the Gordon Malaria Conference in Spain. Connecting with colleagues from around the world and being able to travel a bit for fun was definitely rejuvenating.

Relaxing after a hard day’s work: Spending time with family and friends and watching TV on my couch.

Joelle I. Rosser, MD

Research focus: Impact of climate change on infectious diseases: evaluating interventions to ameliorate the risks of climate change and foster resiliency and sustainability, employing a combination of field studies and modeling to conduct research. The focus is on populations that are highly vulnerable to climate change in the Asia-Pacific.

How the research advances the field: Climate change poses the greatest threat to human health globally. However, the study of climate change and health — predicting and mitigating the impacts on human health — is still in its infancy. My research focuses on developing new approaches to rigorously studying climate change and health, using a mechanism-based framework and a solution-oriented mindset.

Funding: K23 Career Development Award ($996,0000)

Joelle I. Rosser, MD

Joelle I. Rosser, MD

Joelle I. Rosser, MD

Research focus: Impact of climate change on infectious diseases: evaluating interventions to ameliorate the risks of climate change and foster resiliency and sustainability, employing a combination of field studies and modeling to conduct research. The focus is on populations that are highly vulnerable to climate change in the Asia-Pacific.

How the research advances the field: Climate change poses the greatest threat to human health globally. However, the study of climate change and health — predicting and mitigating the impacts on human health — is still in its infancy. My research focuses on developing new approaches to rigorously studying climate change and health, using a mechanism-based framework and a solution-oriented mindset.

Funding: K23 Career Development Award ($996,0000)

Joelle combines a capacity to identify, interpret, and critically consider key scientific findings in the literature with a commitment to use the scientific process to improve the lives of low-income marginalized communities globally.

Stephen Luby, professor of medicine, infectious disease; associate dean for global health research

What the future holds: Continuing my academic research in climate change and infectious diseases with hopes of getting a faculty position somewhere.

Preference: Clinical or research? This is a very difficult question. I love both. They are fundamentally different but also completely complementary. I love interacting with patients, learning about their lives, and working to make their lives better in a very tangible and gratifying way. But I also love the exploration and creativity that research affords. With research, every day feels like a new adventure, a new opportunity. But what makes the research feel worthwhile is also imagining how it might benefit people and the planet in some way later down the road.

Why a career as a physician-scientist? I wanted to be a primatologist. But while studying wildlife conservation, my deepening appreciation for the interdependency between the environment and human health drove me to become a physician-scientist working at this intersection. I also suppose one could argue that by studying medicine, I still did become a primatologist of sorts, just not studying the kind of primate that typically swings from trees.

For the love of science: I love that I get to work with brilliant, caring people with all sorts of different skills and backgrounds. My work is inherently interdisciplinary, and I love learning from and sharing with people across a whole range of expertise.

Active relaxation: Biking, hiking, pack rafting, Latin dancing, windsurfing, challenging my husband to a fierce game of backgammon, and trying to find the best cheese, scones, and hole-in-the-wall music venues.

Translational Investigators — the Future of Team Science

Translational Investigators — the Future of Team Science

Translational Investigators — the Future of Team Science

Given their dual scientific and clinical talents, TIP trainees are perfectly poised to advance the basic understanding, diagnosis, and new treatment of human disease.

“The Translational Investigators Program (TIP) stood out to me because of the unique culture of innovation and discovery that is infused across campus. There’s not only a history of discovery — there’s a palpable sense that Stanford is on the tip of changing the practice of medicine,” says Chad Weldy, MD, PhD, a graduate of the program, who is now a cardiologist and faculty member in the division of cardiovascular medicine and the Stanford Center for Inherited Cardiovascular Disease.

New TIP members are welcomed into the vibrant community of established physician-scientists at Stanford. They join the more senior trainees in both formal and informal meetings to exchange ideas with a range of faculty. The Pathways of Distinction initiative allows them to select a track that best aligns with their academic interests. All interns are paired with mentors who best suit their career interests.

Monthly events are held for TIP members at every training level. Activities range from discussions with leading investigators to skill-based sessions, such as learning how to write successful grant applications. In addition, numerous social events promote a sense of community and offer opportunities to exchange ideas and form bonds across disciplines.

“We are committed to fostering the growth of physician-scientists as they tackle the greatest challenges in medicine,” says Joshua Knowles, MD, PhD, associate professor of medicine and one of the co-directors of the program. “Given their dual scientific and clinical talents, TIP trainees are perfectly poised to advance the basic understanding, diagnosis, and new treatment of human disease,” adds fellow program director Alice Fan, MD, PhD, assistant professor of medicine.

The TIP directors were especially excited to welcome this year’s class of interns, having successfully recruited a group with a wide range of backgrounds, experiences, training, and perspectives that will provide fertile ground for their careers as team scientists.

MEET SOME 2023 TIP INTERNS

Reem Elorbany

Shannon Esswein

Sunil K. Joshi

Christine McIntosh

Raman Nelakanti

Axel Stenmark Tullberg

Jimmy Zheng

Reem Elorbany

Pronouns: She/Her/Hers
Age: 29 years old
Hometown: Milwaukee, WI / Chicago, IL

Languages Spoken at Home:
English, Arabic

Hobbies:
3D printing, Dungeons and Dragons, science fiction novels, crossword puzzles.

Research Field:
Cardiology

What was a formative experience that led you to your career path?
When I was 6, I had an illness that put me into the hospital for a month. The confusion around my diagnosis and lack of patient communication made a big impression on me and ultimately led me to this path.

What drew you to Stanford?
Stanford had the combination of strength in clinical care, scientific research, and education that I was looking for.

Reem Elorbany

Pronouns: She/Her/Hers
Age: 29 years old
Hometown: Milwaukee, WI / Chicago, IL

Languages Spoken at Home:
English, Arabic

Hobbies:
3D printing, Dungeons and Dragons, science fiction novels, crossword puzzles.

Research Field:
Cardiology

What was a formative experience that led you to your career path?
When I was 6, I had an illness that put me into the hospital for a month. The confusion around my diagnosis and lack of patient communication made a big impression on me and ultimately led me to this path.

What drew you to Stanford?
Stanford had the combination of strength in clinical care, scientific research, and education that I was looking for.

Shannon Esswein

Pronouns: She/Her/Hers
Age: 30 years old
Hometown: Simi Valley, CA

Languages Spoken at Home:
English

Hobbies:
I enjoy piano, rock climbing, reading, writing, supporting women in STEM, and spending time with my cats.

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
My experiences of seeing one of my best friends and my mother battling cancer led me to pursue a career as a physician-scientist to care for patients with difficult diagnoses while also developing new therapeutics.

What drew you to Stanford?
Stanford has excellent clinical training and strong research opportunities while also being close to my family in California.

Shannon Esswein

Pronouns: She/Her/Hers
Age: 30 years old
Hometown: Simi Valley, CA

Languages Spoken at Home:
English

Hobbies:
I enjoy piano, rock climbing, reading, writing, supporting women in STEM, and spending time with my cats.

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
My experiences of seeing one of my best friends and my mother battling cancer led me to pursue a career as a physician-scientist to care for patients with difficult diagnoses while also developing new therapeutics.

What drew you to Stanford?
Stanford has excellent clinical training and strong research opportunities while also being close to my family in California.

Sunil K. Joshi

Pronouns: He/Him/His
Age: 34 years old
Hometown: Fairfield, CA

Languages Spoken at Home:
Hindi, Punjabi

Hobbies:
Being in the outdoors, hanging out with family and friends, working out, running

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
Serving as my grandfather’s caretaker as he fought terminal prostate cancer ignited my interest in medicine. I chose to pursue an MD/PhD to deepen my understanding of cancer biology and to advance treatment options.

What drew you to Stanford?
I was drawn by the collaborative spirit and the translational research, with access to world-renowned scientists and state-of-the-art facilities.

Sunil K. Joshi

Pronouns: He/Him/His
Age: 34 years old
Hometown: Fairfield, CA

Languages Spoken at Home:
Hindi, Punjabi

Hobbies:
Being in the outdoors, hanging out with family and friends, working out, running

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
Serving as my grandfather’s caretaker as he fought terminal prostate cancer ignited my interest in medicine. I chose to pursue an MD/PhD to deepen my understanding of cancer biology and to advance treatment options.

What drew you to Stanford?
I was drawn by the collaborative spirit and the translational research, with access to world-renowned scientists and state-of-the-art facilities.

Christine McIntosh

Pronouns: She/Her/Hers
Age: 31 years old
Hometown: Clifton, NJ

Languages Spoken at Home:
English, Croatian

Hobbies:
Cooking, hanging out with our American Forest Cat “Bubba.” I was also a competitive fencer throughout college.

Research Field:
Gastroenterology

What was a formative experience that led you to your career path?My first research mentor was a physician-scientist who discussed clinical questions in our lab meetings. I was inspired by his passion for research, as I could see myself applying my love for molecular and cellular biology toward real-world problems.

What drew you to Stanford?
I fell in love with Stanford during my residency interview day. I met with incredible clinicians and scientists and found it so easy to discuss my research and career goals.

Christine McIntosh

Pronouns: She/Her/Hers
Age: 31 years old
Hometown: Clifton, NJ

Languages Spoken at Home:
English, Croatian

Hobbies:
Cooking, hanging out with our American Forest Cat “Bubba.” I was also a competitive fencer throughout college.

Research Field:
Gastroenterology

What was a formative experience that led you to your career path?
My first research mentor was a physician-scientist who discussed clinical questions in our lab meetings. I was inspired by his passion for research, as I could see myself applying my love for molecular and cellular biology toward real-world problems.

What drew you to Stanford?
I fell in love with Stanford during my residency interview day. I met with incredible clinicians and scientists and found it so easy to discuss my research and career goals.

Raman Nelakanti

Pronouns: He/Him/His
Age: 31 years old
Hometown: Sunnyvale, CA

Languages Spoken at Home:
Telugu and English

Hobbies:
I love hiking with my partner and my dog Sandy. I also sing, garden, and play cricket.

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
I became interested in a physician-scientist career while working as an undergraduate at Stanford in Dr. Joseph Wu’s lab in Cardiovascular Medicine.

What drew you to Stanford?
As an undergraduate at Stanford, I loved the warm, collaborative culture. It’s really come full circle going from volunteering as a pre-med at the SCVMC to practicing as a resident at the same hospitals where my friends and family have been treated.

Raman Nelakanti

Pronouns: He/Him/His
Age: 31 years old
Hometown: Sunnyvale, CA

Languages Spoken at Home:
Telugu and English

Hobbies:
I love hiking with my partner and my dog Sandy. I also sing, garden, and play cricket.

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
I became interested in a physician-scientist career while working as an undergraduate at Stanford in Dr. Joseph Wu’s lab in Cardiovascular Medicine.

What drew you to Stanford?
As an undergraduate at Stanford, I loved the warm, collaborative culture. It’s really come full circle going from volunteering as a pre-med at the SCVMC to practicing as a resident at the same hospitals where my friends and family have been treated.

Axel Stenmark Tullberg

Pronouns: He/Him/His
Age: 29 years old
Hometown: Gothenburg, Sweden

Languages Spoken at Home:
Swedish

Hobbies:
Road cycling, sports, outdoor activities

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
Writing my master’s thesis as a medical student. I knew then I wanted to dedicate my career to oncology and research.

What drew you to Stanford?
The fantastic research opportunities and fit in terms of my research interests. I look forward to connecting with research mentors and becoming part of such a world-class research institute.

Axel Stenmark Tullberg

Pronouns: He/Him/His
Age: 29 years old
Hometown: Gothenburg, Sweden

Languages Spoken at Home:
Swedish

Hobbies:
Road cycling, sports, outdoor activities

Research Field:
Hematology and Oncology

What was a formative experience that led you to your career path?
Writing my master’s thesis as a medical student. I knew then I wanted to dedicate my career to oncology and research.

What drew you to Stanford?
The fantastic research opportunities and fit in terms of my research interests. I look forward to connecting with research mentors and becoming part of such a world-class research institute.

Jimmy Zheng

Pronouns: He/Him/His
Age: 28 years old
Hometown: Saratoga, CA

Languages Spoken at Home:
Mandarin Chinese, English

Hobbies:
Traveling, fitness, coffee shops, amusement parks

Research Field:
Cardiology

What was a formative experience that led you to your career path?
Serving as CFO of a mobile health clinic for homeless and housing-insecure communities in Los Angeles inspired me to become a physician to care for underserved patients.

What drew you to Stanford?
Phenomenal clinical research faculty, impressive cardiology footprint, proximity to family, and impeccable weather.

Jimmy Zheng

Pronouns: He/Him/His
Age: 28 years old
Hometown: Saratoga, CA

Languages Spoken at Home:
Mandarin Chinese, English

Hobbies:
Traveling, fitness, coffee shops, amusement parks

Research Field:
Cardiology

What was a formative experience that led you to your career path?
Serving as CFO of a mobile health clinic for homeless and housing-insecure communities in Los Angeles inspired me to become a physician to care for underserved patients.

What drew you to Stanford?
Phenomenal clinical research faculty, impressive cardiology footprint, proximity to family, and impeccable weather.

Pause, Reflect, and Begin Again

Pause, Reflect, and Begin Again

Pause, Reflect, and Begin Again

Through these selected videos, Department of Medicine staff members take a moment to pause and reflect on how they replenish their energy at work and in their personal lives. They look back on particular experiences in the department that, for them, signify positive change.

Their responses embody the very spirit of renewal: recognizing what has been lost in recent years, looking ahead to 2023–24 with a sense of optimism, and expressing a will and readiness to begin again.

We invite you to join our staff in enacting a collective renewal.

Together, we

  • acknowledge the cyclical nature of life, from loss and mourning to growth and celebration;

  • balance reflecting on the past with hope for a brighter future; and

  • recommit to our shared mission of research, education, clinical care, and community partnership.

Paid Summer Internship Program Furthers Stanford Commitment to Diversity, Equity, Inclusion

Front row, from left: Josue Parra, UC Berkeley; Briana Giglio, San Jose State University; Sarah Morales, UC Berkeley; Daphney Saviotti-Orozco, UC Berkeley. Back row, from left: Cecile Bonini and Karina Delgado-Carrasco.

Front row, from left: Josue Parra, UC Berkeley; Briana Giglio, San Jose State University; Sarah Morales, UC Berkeley; Daphney Saviotti-Orozco, UC Berkeley. Back row, from left: Cecile Bonini and Karina Delgado-Carrasco

Paid Summer Internship Program Furthers Stanford Commitment to Diversity, Equity, Inclusion

Front row, from left: Josue Parra, UC Berkeley; Briana Giglio, San Jose State University; Sarah Morales, UC Berkeley; Daphney Saviotti-Orozco, UC Berkeley. Back row, from left: Cecile Bonini and Karina Delgado-Carrasco.

Front row, from left: Josue Parra, UC Berkeley; Briana Giglio, San Jose State University; Sarah Morales, UC Berkeley; Daphney Saviotti-Orozco, UC Berkeley. Back row, from left: Cecile Bonini and Karina Delgado-Carrasco

Paid Summer Internship Program Furthers Stanford Commitment to Diversity, Equity, Inclusion

During the summer of 2023, the Department of Medicine launched a Paid Internship Program for college students. Through this initiative, eight undergraduates from local universities were placed in staff positions across four divisions in the department.

In the interview that follows, Cecile Bonini, associate director of human resources, and Karina Delgado-Carrasco, director of education programs, answer questions about why the program was established and what it hopes to achieve in the future.

What is the Paid Internship Program?

Bonini: The Paid Internship Program creates summer staff positions for a diverse group of students with a strong appreciation for diversity, equity, inclusion, and belonging (DEIB), who are interested in careers in health care, academic medicine, and administrative roles in higher learning.

How did you go about setting it up?

Bonini: Karina and I reached out to student advisers at local schools and universities to seek applicants with relevant majors. We also contacted campus student support centers and “first-gen” offices, to reach students who were first in their families to attend college.

We promoted the availability of the internships to all 15 divisions in our department. We then developed job descriptions with managers who were excited about supervising a student in a staff role within their work groups.

For this past summer, we had six managers sign on to train and supervise a student. We hired eight people from San Jose State University, UC Berkeley, and the University of San Francisco. Hopefully, these students will view us as a potential employer when they graduate.

What led to the creation of the Paid Internship Program?

Bonini: Two events occurred in 2021. First, the results of a university-wide equity, diversity, and inclusion survey were published. The data showed that though there are spaces at Stanford that can be welcoming and inclusive for many, we have a long way to go as a university to achieve broad-based inclusivity and belonging for all members of the Stanford community.

And second, I noticed that many of the undergraduate students attending our virtual job fairs were asking about paid summer positions. Though we did have summer traineeships available, they were often unpaid or had already been filled by the specific principal investigator seeking those roles.

And how did these two issues motivate you to create this new program?

Bonini: Karina and I felt we could leverage these two scenarios by proactively reaching out to local schools and universities to seek undergraduates who were mission driven; had a strong lens for DEIB; and were interested in health care, academic medicine, or university administration. We would create new summer paid positions with the help of managers who were willing to supervise such individuals on their staff teams.

We approached department leaders who thought this was a wonderful idea. Our director of finance and administration, Cathy Garzio, authorized funding for eight paid summer internships for 2023.

Cecile Bonini (left) and Karina Delgado-Carrasco

Delgado-Carrasco: We also view this program as an opportunity to create a pipeline of candidates who might match a full-time staff role at Stanford in the future. Many students we spoke to were not aware of the numerous employment opportunities we offer; mostly they viewed “health care” as going to medical school or another type of professional training program. Some even thought you had to attend Stanford to work there!

Our goal is to welcome people who otherwise may not have considered working at Stanford and to demonstrate that we have numerous job opportunities for people with a variety of backgrounds and life experiences.

From left: Josue Parra, Briana Giglio, Sarah Morales, Daphney Saviotti-Orozco

During the summer of 2023, the Department of Medicine launched a Paid Internship Program for college students. Through this initiative, eight undergraduates from local universities were placed in staff positions across four divisions in the department.

In the interview that follows, Cecile Bonini, associate director of human resources, and Karina Delgado-Carrasco, director of education programs, answer questions about why the program was established and what it hopes to achieve in the future.

What is the Paid Internship Program?

Bonini: The Paid Internship Program creates summer staff positions for a diverse group of students with a strong appreciation for diversity, equity, inclusion, and belonging (DEIB), who are interested in careers in health care, academic medicine, and administrative roles in higher learning.

How did you go about setting it up?

Bonini: Karina and I reached out to student advisers at local schools and universities to seek applicants with relevant majors. We also contacted campus student support centers and “first-gen” offices, to reach students who were first in their families to attend college.

We promoted the availability of the internships to all 15 divisions in our department. We then developed job descriptions with managers who were excited about supervising a student in a staff role within their work groups.

For this past summer, we had six managers sign on to train and supervise a student. We hired eight people from San Jose State University, UC Berkeley, and the University of San Francisco. Hopefully, these students will view us as a potential employer when they graduate.

Cecile Bonini (left) and Karina Delgado-Carrasco

What led to the creation of the Paid Internship Program?

Bonini: Two events occurred in 2021. First, the results of a university-wide equity, diversity, and inclusion survey were published. The data showed that though there are spaces at Stanford that can be welcoming and inclusive for many, we have a long way to go as a university to achieve broad-based inclusivity and belonging for all members of the Stanford community.

And second, I noticed that many of the undergraduate students attending our virtual job fairs were asking about paid summer positions. Though we did have summer traineeships available, they were often unpaid or had already been filled by the specific principal investigator seeking those roles.

And how did these two issues motivate you to create this new program?

Bonini: Karina and I felt we could leverage these two scenarios by proactively reaching out to local schools and universities to seek undergraduates who were mission driven; had a strong lens for DEIB; and were interested in health care, academic medicine, or university administration. We would create new summer paid positions with the help of managers who were willing to supervise such individuals on their staff teams.

We approached department leaders who thought this was a wonderful idea. Our director of finance and administration, Cathy Garzio, authorized funding for eight paid summer internships for 2023.

Delgado-Carrasco: We also view this program as an opportunity to create a pipeline of candidates who might match a full-time staff role at Stanford in the future. Many students we spoke to were not aware of the numerous employment opportunities we offer; mostly they viewed “health care” as going to medical school or another type of professional training program. Some even thought you had to attend Stanford to work there!

Our goal is to welcome people who otherwise may not have considered working at Stanford and to demonstrate that we have numerous job opportunities for people with a variety of backgrounds and life experiences.

From left: Josue Parra, Briana Giglio, Sarah Morales, Daphney Saviotti-Orozco  

The Paid Internship Program creates summer staff positions for a diverse group of students with a strong appreciation for diversity, equity, inclusion, and belonging, who are interested in careers in health care, academic medicine, and administrative roles in higher learning.

— Cecile Bonini, associate director of human resources

What did this year’s participants do?

Bonini: The eight students worked in various roles in clinical research and administrative support. But it wasn’t all work: We had four professional development seminars that highlighted the importance of personal branding, self-awareness, and networking. Stanford comes with a reputation that some people can find intimidating, so we tried to help the students navigate the organization, ideally so they could envision themselves in full-time roles here in the future. And we had a lovely closing session at the end of the summer, where we bid the students farewell and invited them to keep in touch with one another and with the various connections they made during their time here.

Why do you feel this program is important?

Delgado-Carrasco: Thinking back on my own career journey, I believe having an opportunity like this would have helped me see that there was so much more to do “out there” than I knew about when I was in school. I was a public health major as an undergraduate, but I really didn’t know what that meant in terms of the multiple options I would have for career choices. I felt a little lost back then! I hope this program helps participants understand the numerous roles people who are interested in health care can play.

The Paid Internship Program creates summer staff positions for a diverse group of students with a strong appreciation for diversity, equity, inclusion, and belonging, who are interested in careers in health care, academic medicine, and administrative roles in higher learning.

— Cecile Bonini, associate director of human resources

What did this year’s participants do?

Bonini: The eight students worked in various roles in clinical research and administrative support. But it wasn’t all work: We had four professional development seminars that highlighted the importance of personal branding, self-awareness, and networking. Stanford comes with a reputation that some people can find intimidating, so we tried to help the students navigate the organization, ideally so they could envision themselves in full-time roles here in the future. And we had a lovely closing session at the end of the summer, where we bid the students farewell and invited them to keep in touch with one another and with the various connections they made during their time here.

Why do you feel this program is important?

Delgado-Carrasco: Thinking back on my own career journey, I believe having an opportunity like this would have helped me see that there was so much more to do “out there” than I knew about when I was in school. I was a public health major as an undergraduate, but I really didn’t know what that meant in terms of the multiple options I would have for career choices. I felt a little lost back then! I hope this program helps participants understand the numerous roles people who are interested in health care can play.

From Bariatric Surgeon to Accidental Activist

Arghavan Salles, MD, PhD

Arghavan Salles, MD, PhD

From Bariatric Surgeon to Accidental Activist

How One MD/PhD Harnesses the Power of Social Media for Advocacy and Career Development

Arghavan Salles, MD, PhD

From Bariatric Surgeon to Accidental Activist

How One MD/PhD Harnesses the Power of Social Media for Advocacy and Career Development

Arghavan Salles, MD, PhD, did not set out to be an activist or social media influencer. After completing medical school, a surgery residency, and a PhD in education at Stanford, Salles worked as a bariatric surgeon and faculty member in St. Louis, Missouri. She now looks back on the toll those years of grueling medical service and an unsuccessful fertility journey took on her energy. In 2019, she returned to Stanford and the Bay Area for a change of scene and an opportunity to renew her energy and drive.

Now, Salles is a clinical associate professor of gastroenterology and hepatology and special adviser of diversity, equity, and inclusion programs in the Department of Medicine. She found renewed motivation in an unexpected place: Twitter, which she joined in 2016.

She initially shared academic posts (research papers and bariatric surgery content, for example). Over time, she shared more personal content grounded in her sense of justice and responsibility.

Salles identifies, in her own words, as “an academic physician who does research to shed light on certain problems and push our institutions and society toward more inclusive policies” and uses social media primarily as a useful tool in that context.

Below, Salles reflects on the energy driving her posts and how to use social media as a tool for both advocacy and career advancement.

People say silence is complicity, and I do think that is true to some extent. The more we ignore things, the more we suggest those things are fine.

What drives you to do the work of social media activism each day?

I think what keeps me going is a little bit of naïveté — feeling like we can make a difference, that more people speaking up can shift culture and open people’s eyes to issues.

There’s also a feeling of discomfort and uncertainty. I feel very unsettled about a lot of the things happening in the world. I can’t just sit on the sidelines and be like, Oh, someone else will figure that out. Or, It’s OK if I don’t say anything. The more we ignore things, the more we suggest those things are fine.

I have a very strong sense of justice, which may not align with someone else’s, but it is all mine. What I think is right is something I often want to fight for and speak up about. That desire doesn’t really fade from day to day.

Is there a post that stands out as especially representative of your work?

I had this video in January that was about gender schemas, particularly how we view women’s behavior differently just because they’re women, especially in male-dominated professions and anytime we have to be in authoritative roles. There were many women who were like, This is happening every day of my life. They didn’t know the research around this, so my post was validating for them.

There’s a lot we don’t talk about publicly. That leaves people feeling alone and isolated. Even though what they are experiencing is something that’s relatively common, it’s not talked about. I try to communicate to the people who need to hear it: If you’re experiencing this, know that other people experience it too. That doesn’t mean it’s OK, and we should try to fix the systems in place that make this a reality. But also, you’re not alone.

A lot of what I’ve been doing in the last year or so has been about pushing the boundaries of what we think of as professionalism. In most of our organizations, professionalism is weaponized against marginalized people. And it’s really all just made up.

For example, in an Instagram reel I posted in March about being a surgeon with hyper-colored hair, I talk about how I can show up to a place, wearing clean clothes, having showered, having my hair done, whatever, and just because the color of my hair is different than what people are used to, that makes me not professional. So I believe that people should have autonomy over their bodies. It’s not harming anyone else, and it’s not affecting their ability to do their jobs.

What advice would you offer to academics interested in becoming more active on social media, and perhaps in doing advocacy on social platforms?

It’s such an interesting time. Two years ago, I might have said everyone should be on Twitter. But Twitter [rebranded as X in July 2023] is evolving, right? Not necessarily in a positive direction, so it’s hard for me to say that now.

But what I can say is that those of us who are on Twitter have developed collaborations from being in that space. We’ve made friends, and we’ve built community. I’ve found mentors through Twitter who I wouldn’t have met otherwise. I met most of the collaborators on my R01 grant, “Sexual Harassment Training of Primary Investigators (STOP),” via social media.

Social media can be a powerful tool for career development, especially when people are thinking about promotions to associate or full professor, and it can help in developing a regional or national reputation (especially for people who don’t focus on academic publishing).

I don’t think it has to be about activism for everyone. There’s value in networking and in accessing information and scientific research. I think social media is more effective for keeping up on the latest science than going from journal to journal or newspaper to newspaper. Information on research, clinical trials, and the latest things you need to know about the practice of medicine is much more accessible on social media.

People say silence is complicity, and I do think that is true to some extent. The more we ignore things, the more we suggest those things are fine.

Salles identifies, in her own words, as “an academic physician who does research to shed light on certain problems and push our institutions and society toward more inclusive policies” and uses social media primarily as “a useful tool in that context.”

Below, Salles reflects on the energy driving her posts and how to use social media as a tool for both advocacy and career advancement.

What drives you to do the work of social media activism each day?

I think what keeps me going is a little bit of naïveté — feeling like we can make a difference, that more people speaking up can shift culture and open people’s eyes to issues.

There’s also a feeling of discomfort and uncertainty. I feel very unsettled about a lot of the things happening in the world. I can’t just sit on the sidelines and be like, Oh, someone else will figure that out. Or, It’s OK if I don’t say anything. The more we ignore things, the more we suggest those things are fine.

I have a very strong sense of justice, which may not align with someone else’s, but it is all mine. What I think is right is something I often want to fight for and speak up about. That desire doesn’t really fade from day to day.

Is there a post that stands out as especially representative of your work?

I had this video in January that was about gender schemas, particularly how we view women’s behavior differently just because they’re women, especially in male-dominated professions and anytime we have to be in authoritative roles. There were many women who were like, This is happening every day of my life. They didn’t know the research around this, so my post was validating for them.

There’s a lot we don’t talk about publicly. That leaves people feeling alone and isolated. Even though what they are experiencing is something that’s relatively common, it’s not talked about. I try to communicate to the people who need to hear it: If you’re experiencing this, know that other people experience it too. That doesn’t mean it’s OK, and we should try to fix the systems in place that make this a reality. But also, you’re not alone.

A lot of what I’ve been doing in the last year or so has been about pushing the boundaries of what we think of as professionalism. In most of our organizations, professionalism is weaponized against marginalized people. And it’s really all just made up.

For example, in an Instagram reel I posted in March about being a surgeon with hyper-colored hair, I talk about how I can show up to a place, wearing clean clothes, having showered, having my hair done, whatever, and just because the color of my hair is different than what people are used to, that makes me not professional. So I believe that people should have autonomy over their bodies. It’s not harming anyone else, and it’s not affecting their ability to do their jobs.

What advice would you offer to academics interested in becoming more active on social media, and perhaps in doing advocacy on social platforms?

It’s such an interesting time. Two years ago, I might have said everyone should be on Twitter. But Twitter [rebranded as X in July 2023] is evolving, right? Not necessarily in a positive direction, so it’s hard for me to say that now.

But what I can say is that those of us who are on Twitter have developed collaborations from being in that space. We’ve made friends, and we’ve built community. I’ve found mentors through Twitter who I wouldn’t have met otherwise. I met most of the collaborators on my R01 grant, “Sexual Harassment Training of Primary Investigators (STOP),” via social media.

Social media can be a powerful tool for career development, especially when people are thinking about promotions to associate or full professor, and it can help in developing a regional or national reputation (especially for people who don’t focus on academic publishing).

I don’t think it has to be about activism for everyone. There’s value in networking and in accessing information and scientific research. I think social media is more effective for keeping up on the latest science than going from journal to journal or newspaper to newspaper. Information on research, clinical trials, and the latest things you need to know about the practice of medicine is much more accessible on social media.

SCCR’s Quality and Compliance Team Shows Resilience Amid Pandemic Pivots

Mary Varkey, clinical research coordinator, with a RECOVER participant
Mary Varkey, clinical research coordinator, with a RECOVER participant.

SCCR’s Quality and Compliance Team Shows Resilience Amid Pandemic Pivots

Mary Varkey, clinical research coordinator, with a RECOVER participant
Mary Varkey, clinical research coordinator, with a RECOVER participant.

SCCR’s Quality and Compliance Team Shows Resilience Amid Pandemic Pivots

When COVID-19 hit in 2020, it dramatically disrupted ongoing clinical research, as well as quality and compliance monitoring.

The Quality and Compliance team at the Stanford Center for Clinical Research (SCCR) faced the challenges head-on, pivoting and pivoting again as the situation on the ground shifted. By the time the brunt of the pandemic ended, the Department of Medicine had a larger clinical research portfolio than ever — from $125.7 million in sponsored research in 2019 to $164 million in 2022, and quality and compliance monitoring had entered a new era.

Essential Trials Go Virtual

When COVID hit, the university paused nonessential research, a category that included observational clinical trials unrelated to COVID.

The majority of studies that SCCR participates in are interventional, however, and remained active. At the same time, many new studies that were focused on understanding and treating COVID launched across the department. The SCCR Quality and Compliance team quickly learned how to operate in the new virtual paradigm.

Study monitoring that had been done on-site went remote. Teams moved to use electronic consent forms that participants could sign remotely or on encrypted iPads with plastic covers that could be cleaned after each use. If paper consent forms had to be used, staff took photos of the signature pages for study records. They then quarantined the paper forms for 10 days in sealed bags before removing and filing. Checklists became an essential tool to ensure that study conduct remained as methodical and precise in the new, shifting paradigm as it was prior to COVID.

Restarting Research and Refreshing Protocols

When it was time to resume paused studies, study teams received refreshers on the study protocol, consenting processes, and data entry.

Some studies resumed before pandemic restrictions had entirely lifted. One such study was the Project Baseline study — a large, multiyear observational study that aims to map human health. The project was paused for seven months and then resumed with virtual operations.

The study team worked with the research sponsor to build systems to conduct virtual study visits and temporarily waive on-site assessments. They often met with participants over video to help them through study processes that would typically be done face-to-face.

Kelly Olszewski, clinical research coordinator, explains the RECOVER study process.

In February 2021, as vaccines became available, Project Baseline was able to resume some onsite visits for assessments such as specimen collection, vital signs, and EKGs.

The study team’s resilience in the face of multiple hurdles kept the research project alive against the odds. “Retention for this seminal, longitudinal Team Science study remains high (88%) as we approach the end of the study,” says Sumana Shashidhar, SCCR’s associate director of clinical research operations. (Read about Shashidhar’s work with a Johnson & Johnson vaccine study in this Stanford Daily Q&A.)

Yasmin Jazayeri, clinical research coordinator, gathers data for the RECOVER study

When COVID-19 hit in 2020, it dramatically disrupted ongoing clinical research, as well as quality and compliance monitoring.

The Quality and Compliance team at the Stanford Center for Clinical Research (SCCR) faced the challenges head-on, pivoting and pivoting again as the situation on the ground shifted. By the time the brunt of the pandemic ended, the Department of Medicine had a larger clinical research portfolio than ever — from $125.7 million in sponsored research in 2019 to $164 million in 2022, and quality and compliance monitoring had entered a new era.

Essential Trials Go Virtual

When COVID hit, the university paused nonessential research, a category that included observational clinical trials unrelated to COVID.

The majority of studies that SCCR participates in are interventional, however, and remained active. At the same time, many new studies that were focused on understanding and treating COVID launched across the department. The SCCR Quality and Compliance team quickly learned how to operate in the new virtual paradigm.

Study monitoring that had been done on-site went remote. Teams moved to use electronic consent forms that participants could sign remotely or on encrypted iPads with plastic covers that could be cleaned after each use. If paper consent forms had to be used, staff took photos of the signature pages for study records. They then quarantined the paper forms for 10 days in sealed bags before removing and filing. Checklists became an essential tool to ensure that study conduct remained as methodical and precise in the new, shifting paradigm as it was prior to COVID.

Kelly Olszewski, clinical research coordinator, explains the RECOVER study process.

Restarting Research and Refreshing Protocols

When it was time to resume paused studies, study teams received refreshers on the study protocol, consenting processes, and data entry.

Some studies resumed before pandemic restrictions had entirely lifted. One such study was the Project Baseline study — a large, multiyear observational study that aims to map human health. The project was paused for seven months and then resumed with virtual operations.

The study team worked with the research sponsor to build systems to conduct virtual study visits and temporarily waive on-site assessments. They often met with participants over video to help them through study processes that would typically be done face-to-face.

In February 2021, as vaccines became available, Project Baseline was able to resume some onsite visits for assessments such as specimen collection, vital signs, and EKGs.

The study team’s resilience in the face of multiple hurdles kept the research project alive against the odds. “Retention for this seminal, longitudinal Team Science study remains high (88%) as we approach the end of the study,” says Sumana Shashidhar, SCCR’s associate director of clinical research operations. (Read about Shashidhar’s work with a Johnson & Johnson vaccine study in this Stanford Daily Q&A.)

We learned a lot during the pandemic about how we can simplify research conduct and maintain high scientific rigor, quality, and compliance. 

— Ken Mahaffey, MD, SCCR director and department vice chair of research

Yasmin Jazayeri, clinical research coordinator, gathers data for the RECOVER study.

COVID-19 Leaves an Electronic Legacy…

As pandemic restrictions lift, some of the quality and compliance processes created in response to the COVID lockdown have become standard practice. For example, it’s increasingly common to gather participant consent forms electronically and to keep trial documentation in electronic trial master files instead of binders.

“We learned a lot during the pandemic about how we can simplify research conduct and maintain high scientific rigor, quality, and compliance,” says SCCR director and department vice chair of research Ken Mahaffey, MD. “I am incredibly proud of the work that the SCCR Quality and Compliance team has done.”

…and a Clinical Research Legacy

As teams across the department launched COVID-19 studies, SCCR’s regulatory team partnered with investigators to swiftly submit Investigational New Drug (IND) applications to the FDA.

“We launched nearly 20 COVID-19 projects seemingly overnight,” says Toni Nunes, SCCR’s director of operations and strategy.

In 2020, for example, SCCR participated in the Ensemble trial of the Janssen COVID-19 vaccine, enrolling 205 participants in two months. SCCR also operationalized the RECOVER study at Stanford, a National Institutes of Health–funded initiative to study the long-term effects of COVID.

Though COVID threw a logistical curveball at researchers and quality and compliance monitors alike, the pandemic ultimately contributed to growth in clinical research across the department, bringing in organizations and faculty members who had never done research before and now were doing research on COVID and beyond.

A prime example is Stanford Health Care Tri-Valley Hospital (SHC Tri-Valley). In 2020, SHC Tri-Valley hospitalists participated in a trial of treatments for people hospitalized with COVID, with support from SCCR. A series of COVID studies based at SHC Tri-Valley followed, including TRACK COVID, a public health surveillance study. In 2022, SHC Tri-Valley became a site for the Medtronic Ellipsys Vascular Access System Post Market Surveillance Study. The trial evaluates the safety and effectiveness of the Ellipsys Vascular Access System, a device used to create vascular access for hemodialysis — and has nothing to do with COVID.

We learned a lot during the pandemic about how we can simplify research conduct and maintain high scientific rigor, quality, and compliance. 

— Ken Mahaffey, MD, SCCR director and department vice chair of research

 

COVID-19 Leaves an Electronic Legacy…

As pandemic restrictions lift, some of the quality and compliance processes created in response to the COVID lockdown have become standard practice. For example, it’s increasingly common to gather participant consent forms electronically and to keep trial documentation in electronic trial master files instead of binders.

“We learned a lot during the pandemic about how we can simplify research conduct and maintain high scientific rigor, quality, and compliance,” says SCCR director and department vice chair of research Ken Mahaffey, MD. “I am incredibly proud of the work that the SCCR Quality and Compliance team has done.”

…and a Clinical Research Legacy

As teams across the department launched COVID-19 studies, SCCR’s regulatory team partnered with investigators to swiftly submit Investigational New Drug (IND) applications to the FDA.

“We launched nearly 20 COVID-19 projects seemingly overnight,” says Toni Nunes, SCCR’s director of operations and strategy.

In 2020, for example, SCCR participated in the Ensemble trial of the Janssen COVID-19 vaccine, enrolling 205 participants in two months. SCCR also operationalized the RECOVER study at Stanford, a National Institutes of Health–funded initiative to study the long-term effects of COVID.

Though COVID threw a logistical curveball at researchers and quality and compliance monitors alike, the pandemic ultimately contributed to growth in clinical research across the department, bringing in organizations and faculty members who had never done research before and now were doing research on COVID and beyond.

A prime example is Stanford Health Care Tri-Valley Hospital (SHC Tri-Valley). In 2020, SHC Tri-Valley hospitalists participated in a trial of treatments for people hospitalized with COVID, with support from SCCR. A series of COVID studies based at SHC Tri-Valley followed, including TRACK COVID, a public health surveillance study. In 2022, SHC Tri-Valley became a site for the Medtronic Ellipsys Vascular Access System Post Market Surveillance Study. The trial evaluates the safety and effectiveness of the Ellipsys Vascular Access System, a device used to create vascular access for hemodialysis — and has nothing to do with COVID.